The All of Us Research Program is building a dataset to help transform the future of health research by equipping researchers with expansive health data shared by a diverse participant cohort. The All of Us dataset is disease agnostic and can support research on many aspects of health.
Thousands of health researchers are already leveraging this one-of-a-kind dataset to improve understanding of health and disease, identify opportunities to reduce disparities, and enable more precise approaches to care.
On this page:
About the Research Hub
Benefits for Researchers
Guidelines for Applicants
Funding Opportunities
About the Research Hub
The All of Us Research Hub stores health data from a diverse group of participants from across the United States. Visit the Research Hub to:
- Use the interactive Data Browser. The Data Browser provides interactive views of the publicly available All of Us Research Program participant data. Currently, participant-provided information, including data from surveys, wearables, physical measurements taken at the time of participant enrollment, and electronic health records (EHRs), is available.
- View Data Snapshots. These aggregated, public-facing data snapshots provide an overview of All of Us Research Program participant characteristics and the types of data that the program collects from participants.
- Read about All of Us data sources and methods of data curation.
- Find information about privacy and security processes that help keep participant data safe.
The Research Hub also houses the Researcher Workbench platform and its suite of custom tools. The Workbench offers access to additional levels of data, workspaces, a cohort builder, and an interactive notebook environment. These tools are available to registered All of Us researchers.
Only researchers whose institutions have signed a Data Use and Registration Agreement (DURA) may register for the Researcher Workbench. This agreement must be signed by an institutional signing official. You can check if your institution has access by visiting the Research Hub.
Benefits for Researchers
The All of Us Research Program’s centralized, secure, cloud-based platform allows researchers across a wide range of settings and institutions and at all stages of their careers (e.g., students, early-stage investigators) to execute rapid, hypothesis-driven research with just a computer and an Internet connection.
All of Us facilitates equity in access in a deliberately inclusive way, creating a demographically diverse researcher cohort.
Researcher Access to Genomic Data
Within the Researcher Workbench's Controlled Tier, data from nearly 250,000 whole genome sequences and more than 312,900 genotyping arrays are integrated alongside data from surveys, physical measurements, EHRs, and wearables. The data and tools are available only to registered researchers who have taken additional steps and training to access these data. Using these datasets, researchers have opportunities to:
- Make associations through an integrated dataset by cross-referencing biologic data with data related to participants’ environment and life circumstances
- Build upon the traditional longitudinal study model by layering dense, omic data from a large, diverse population
- Come together with other researchers from different disciplines around project-specific data analysis (through collaborative workspaces, cohort-building tools, interactive notebooks, etc.)
- Learn from sample cohorts for replicability and to help get started
- Leverage innovations of other studies and cohorts
Guidelines for Applicants to Funding Opportunities
To help promote equal opportunity for researchers to use All of Us resources, a core value of the program, we’ve assembled guidance for prospective applicants.
Data Resources
Participants share data from multiple sources. The All of Us Research Program’s Data and Research Center curates and validates these data as part of the data collection process. Not all of these data are currently available to researchers, but as the program grows, additional data sources will become available. An NIH Letter of Support from All of Us is NOT necessary if a researcher is seeking funding to use the data available on the Researcher Workbench.
Available data types include:
- More than 413,350 survey responses
- More than 337,500 physical measurements
- More than 312,900 genotyping arrays
- More than 287,000 electronic health records (EHRs)
- More than 245,350 whole genome sequences
- More than 15,600 Fitbit records
- More than 1,000 long-read whole genome sequences
All of Us Resources Beyond Data
Biospecimens
Access to biospecimens for partnered research studies is not yet widely available. When the program opens access to biospecimens, we will require an NIH Letter of Support from All of Us. To help researchers prepare, the approximate date range when requests for access will start to be considered will be announced, along with more information on the procedures, policies, and requirements for access.
Participants
Access to participants for partnered research studies is not yet widely available. Once this access is available, it will require an NIH Letter of Support from All of Us. To help researchers prepare, the approximate date range when requests for access will start to be considered will be announced, along with more information on the procedures, policies, and requirements for access.
Access of All of Us Operations
Studying the All of Us Research Program's structure and/or programmatic activities is not currently supported. The approximate date range when requests for access will start to be considered will be announced to help researchers prepare, along with more information on the procedures, policies, and requirements for access.
Funding Opportunities
All of Us Funding Opportunities
NIH Funding for All of Us Researchers
Learn more through the research projects and publications made possible by All of Us data and tools.
Questions? Contact us.
